北京桑拿网 北京品茶网 喝茶约茶 北京夜生活论坛国产成人综合自拍_欧美日韩在线视频免费观看_国产高清精品在线_欧美夜夜操_男女在线观看_久久久涩

產(chǎn)品中心

CBP (Acetyl Lys1535) rabbit pAb
一鍵復(fù)制產(chǎn)品信息
ES1095
規(guī)格： 價(jià)格：
50μL ￥1280.00
100μL ￥1980.00

Overview

Product name: CBP (Acetyl Lys1535) rabbit pAb
Reactivity: Human;Mouse;Rat
Alternative Names: CREBBP; CBP; CREB-binding protein
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human CBP around the acetylated site of Lys1535. AA range:1501-1550
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 265kD
GeneID: 1387
Human Swiss-Prot No: Q92793
Cellular localization: Cytoplasm. Nucleus. Recruited to nuclear bodies by SS18L1/CREST. In the presence of ALX1 relocalizes from the cytoplasm to the nucleus.
Background: This gene is ubiquitously expressed and is involved in the transcriptional coactivation of many different transcription factors. First isolated as a nuclear protein that binds to cAMP-response element binding protein (CREB), this gene is now known to play critical roles in embryonic development, growth control, and homeostasis by coupling chromatin remodeling to transcription factor recognition. The protein encoded by this gene has intrinsic histone acetyltransferase activity and also acts as a scaffold to stabilize additional protein interactions with the transcription complex. This protein acetylates both histone and non-histone proteins. This protein shares regions of very high sequence similarity with protein p300 in its bromodomain, cysteine-histidine-rich regions, and histone acetyltransferase domain. Mutations in this gene cause Rubinstein-Taybi syndrome (RTS). Chromosomal translocations invo
關(guān)閉

在線咨詢

Online consultation

  • 在線咨詢
  • 技術(shù)支持

關(guān)注微信公眾號(hào)

微信掃一掃立即咨詢

微信掃一掃立即咨詢

關(guān)閉