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Ezrin rabbit pAb

一鍵復(fù)制產(chǎn)品信息

ES2313

規(guī)格：	價(jià)格：
50μL	￥1280.00
100μL	￥1980.00

下載說(shuō)明 ①

Overview

Product name:	Ezrin rabbit pAb
Reactivity:	Human;Mouse;Rat
Alternative Names:	EZR; VIL2; Ezrin; Cytovillin; Villin-2; p81
Source:	Rabbit
Dilutions:	Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Immunogen:	The antiserum was produced against synthesized peptide derived from human Ezrin. AA range:511-560
Storage:	-20°C/1 year
Clonality:	Polyclonal
Isotype:	IgG
Concentration:	1 mg/ml
Observed Band:	70kD
GeneID:	7430
Human Swiss-Prot No:	P15311
Cellular localization:	Apical cell membrane ; Peripheral membrane protein ; Cytoplasmic side . Cell projection . Cell projection, microvillus membrane ; Peripheral membrane protein ; Cytoplasmic side . Cell projection, ruffle membrane ; Peripheral membrane protein ; Cytoplasmic side . Cytoplasm, cell cortex . Cytoplasm, cytoskeleton . Cell projection, microvillus . Localization to the apical membrane of parietal cells depends on the interaction with PALS1. Localizes to cell extensions and peripheral processes of astrocytes (By similarity). Microvillar peripheral membrane protein (cytoplasmic side). .
Background:	The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene. [provided by RefSeq, Jul 2008],

Western Blot analysis of various cells using Ezrin Polyclonal Antibody diluted at 1:2000
Western Blot analysis of MCF7 cells using Ezrin Polyclonal Antibody diluted at 1:2000
Immunohistochemistry analysis of paraffin-embedded human brain tissue, using Ezrin Antibody. The picture on the right is blocked with the synthesized peptide.
Western blot analysis of lysates from HuvE, MCF-7, HepG2, and HeLa cells, using Ezrin Antibody. The lane on the right is blocked with the synthesized peptide.

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